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There are a total of 17 vehicles in the game: 10 are available from the start, 5 are unlockable, and 2 are unplayable. TM:B has a diverse cast made up from both new and returning vehicles, some of which have changed drastically from their previous appearances. Most drivers are also now asylum patients released by Calypso by unknown means. TM:B is set in a universe far from the world in previous installments, being more graphic, violent, and dark. However, the characters will have to win Calypso's Twisted Metal tournament to make their wishes. They then meet a man named Calypso, whom people believe to have ability to grant anyone's wishes. Most of the characters in the games are being held in Blackfield Asylum, a mental institution.
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All the stories focus on the perspective of each of the characters. TM:B is set in a fictional town named Midtown.
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